CJC-1295 (no DAC) combined with Ipamorelin at a balanced 5mg/5mg ratio is one of the most studied growth-hormone–releasing peptide stacks used in research to examine natural GH pulsatility, metabolic function, cellular repair, recovery pathways, and age-related decline. This synergistic pairing is designed to amplify growth-hormone secretion through both GHRH- and GHRP-based pathways, offering a dual-mechanism model for researchers studying regeneration, fat metabolism, tissue repair, and peptide-based endocrine modulation.
CJC-1295
$80.00
Dual-Pathway GH Stimulation
CJC-1295 (no DAC) acts as a GHRH analog, while Ipamorelin functions as a selective GHRP, allowing two separate receptor systems (GHRH + Ghrelin) to synergize in GH production.
Pulsatile GH Release (No DAC Advantage)
Unlike CJC-1295 DAC, the no-DAC version supports natural GH pulses, which many researchers consider more physiologically relevant for long-term regenerative studies.
Selective Ghrelin Receptor Activation (Ipamorelin)
Ipamorelin preferentially activates the ghrelin receptor without the cortisol or prolactin spikes associated with older GHRPs (GHRP-2 or GHRP-6).
Enhanced IGF-1 Expression
The synergy between CJC-1295 (no DAC) and Ipamorelin contributes to increased liver production of IGF-1—an essential peptide studied in muscle growth, recovery, and cellular repair.
Preservation of Hypothalamic Signaling
This stack preserves endogenous GH feedback mechanisms, preventing the downregulation often seen with synthetic GH administration.
GH/IGF-1 Lipolytic Pathway Activation
Research shows GH and IGF-1 upregulate enzymes involved in fat oxidation and metabolic turnover.
Sleep-Linked GH Pulses
CJC/Ipa is studied for enhancing natural overnight GH secretion when administered before sleep.
What Is CJC-1295 + Ipamorelin?
This combination pairs two of the most respected GH secretagogues in research: CJC-1295 (no DAC), a GHRH analog that stimulates GH from the pituitary, and Ipamorelin, a selective ghrelin receptor agonist known for its clean, cortisol-neutral profile. Together, they create a dual-action model that amplifies natural GH pulses while supporting IGF-1 activation, cellular repair pathways, and metabolic improvement.
Why Choose CJC-1295 + Ipamorelin for Research?
The synergy between CJC-1295 (no DAC) and Ipamorelin is considered one of the most predictable and physiologically relevant ways to study GH enhancement. Instead of forcing unnaturally high GH levels (as seen with DAC), this version allows researchers to model natural pulsation, receptor sensitivity preservation, and circadian GH activity. This makes it ideal for studies involving aging, tissue repair, fat metabolism, mitochondrial regeneration, and hormonal optimization.
Recovery & Tissue Repair
GH pathways are heavily involved in collagen synthesis, tendon repair, and recovery from micro-tears. CJC/Ipa is studied for accelerating post-stress tissue regeneration.
Anti-Aging & Cellular Longevity Studies
Researchers evaluate CJC/Ipa for effects on cell turnover, mitochondrial function, and age-related decline markers.
Fat-Metabolism Pathway Support
GH increases the availability of free fatty acids and enhances metabolic turnover, making this stack popular in metabolic and lipolysis studies.
Natural Hormonal Rhythm Modeling
Because CJC-1295 (no DAC) avoids forced 24-hr elevation, it enables research involving naturalistic GH pulsation.
Muscle Growth & Performance Research
GH/IGF-1 pathways influence hypertrophy mechanisms, making this stack ideal for performance-oriented research studies.
Synergy with Additional Peptides
Frequently combined with Tesamorelin, 5-Amino-1MQ, and MOTS-c for deeper metabolic insights.
Sleep Quality & Circadian Research
GH release peaks during sleep; this stack is commonly studied within sleep-linked recovery pathways.
Healing & Regenerative Biology
Researchers explore its role in soft-tissue recovery, wound-repair, and collagen synthesis.
Improved GH Sensitivity
May enhance receptor responsiveness over time in long-term endocrine studies.
Reduced Side-Effect Profile
Ipamorelin is notable for its selective receptor binding, minimizing unwanted hormonal crossover.



